Tinted Glasses (FL-41)

Summary:
FL-41 and other precision-tinted lenses are designed to block specific wavelengths of light that may trigger migraine attacks or worsen photophobia.

Biological Plausibility

Migraine photophobia is linked to hypersensitivity in retinal and thalamic pathways. FL-41 lenses filter out wavelengths (especially in the blue-green spectrum) most likely to activate these circuits.

Evidence

Multiple small studies suggest FL-41 lenses reduce headache frequency and photophobia severity, especially in pediatric populations. Results are variable and depend on individual sensitivity.

Effect Size

Reported reduction of 1–2 migraine days/month. Around 30–40% of patients report subjective improvement in light tolerance.

⚠️ Risk

Minimal. Some patients may experience temporary visual discomfort when adjusting to new tints.

Cost

$$

Scores

  • Benefit: 2
  • Burden: 3
  • Ratio: 0.67

Clinical Takeaways

  • Best for patients with persistent light sensitivity or screen intolerance.
  • May be used preventively or acutely during exposure to triggering environments.
  • Prescription versions with proper tint calibration are more effective than generic options.

Key References

  • Wilkins AJ, et al. *Tinted spectacles and visually sensitive migraine.* Cephalalgia. 2002.
  • Good PA, et al. *Reduction of light sensitivity in migraine with precision ophthalmic tints: A prospective study.* Cephalalgia. 1991.
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