Ear-pressure Device (Zōk)
Summary:
The Zōk device is designed to equalize pressure in the middle ear and stimulate the vagus and trigeminal nerves through the ear canal, aiming to abort or reduce migraine symptoms.
Biological Plausibility
The vagus and trigeminal nerves both innervate portions of the external ear and are implicated in migraine pathophysiology. Theoretical benefit may arise from autonomic modulation or mechanical vagal stimulation, but specific mechanistic data is lacking.
Evidence
No peer-reviewed studies have evaluated Zōk or similar devices for migraine. Claims are based on user testimonials and extrapolation from vagus nerve stimulation research.
Effect Size
Unknown. Anecdotal reports suggest benefit in some users, but no controlled trials exist to establish efficacy.
⚠️ Risk
Minimal. Possible discomfort, temporary hearing changes, or improper use effects. Long-term safety is unknown.
Cost
$$
Scores
- Benefit: 0
- Burden: 2
- Ratio: 0.0
Clinical Takeaways
- No clinical evidence to support use.
- May appeal to patients seeking drug-free relief.
- Should not be used as a primary treatment without further research.
Key References
- No published studies currently available. Claims are extrapolated from vagus nerve and baroreceptor stimulation literature.